The secretor locus as a marker for prenatal prediction of myotonic dystrophy (DM)

✍ Scribed by J. Greiner; D. H. Spengler; J. Krüger; G. Tariverdian

• Book ID: 104707595
• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 249 KB
• Volume: 78
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00291729

✦ Synopsis

To verify the reliability of secretor status for prenatal diagnosis of myotonic dystrophy (DM), 179 amniotic fluid samples were compared with saliva or urine samples of the infants by hemagglutination inhibition. While no discrepancies were observed, problems could arise with intermediate results. Additionally, secretor typing is only informative in 8.4% of patients.