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The secondary structure of human amyloid deposits as determined by circular dichroism spectroscopy

✍ Scribed by Michael Cascio; Paul A. Glazer; B.A. Wallace


Book ID
115761557
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
436 KB
Volume
162
Category
Article
ISSN
0006-291X

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## Abstract α‐Synuclein (α‐Syn) has been identified as a component of intracellular fibrillar deposits in Parkinson's disease. Though the real pathogenesis is still unknown, many investigations have revealed that conformational alteration and fibril formation of α‐Syn protein have an important role