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The Scope and Mechanism of Phosphonium-Mediated SNAr Reactions in Heterocyclic Amides and Ureas

✍ Scribed by Wan, Zhao-Kui; Wacharasindhu, Sumrit; Levins, Christopher G.; Lin, Melissa; Tabei, Keiko; Mansour, Tarek S.


Book ID
111656861
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
574 KB
Volume
72
Category
Article
ISSN
0022-3263

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Bifunctional catalysis by amides and ure
✍ J.M. Briody; D. Narinesingh πŸ“‚ Article πŸ“… 1971 πŸ› Elsevier Science 🌐 French βš– 176 KB

Bifunctional catalysis has been observed in a variety of reactions and the possible role of such catalysis in enzyme systems has been discussed.1 Amides other than 2-pyridone, have not been shown to be effective bifunctional catalysts. 2 We now report evidence for bifunctional catalysis by amides a