An improved capillary membrane fixed enzyme reactor,(CAMFER) model developed earlier (ref.6) was extensively tested by experiments with laboratory and industrial hollow fiber modules for lactose hydrolysis by B-galactosidase. Two capillary internal diameters were used. The industrial cartridges were
The scaling up of mass-transfer equipment and reactors: Use of hydraulic model experiments
✍ Scribed by A.M. Rosen; V.S. Krylov
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- English
- Weight
- 867 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0009-2509
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✦ Synopsis
The loss in efficiency of mass-transfer equipment and chemical reactors when scaling up is explained by the development of transverse non-uniformity in large scale apparatus. This transverse non-uniformity is discussed on the basis of diffusion and channelling models. The probability of velocity fluctuations and consequent concentration gradients is about proportional to the crosssectional area of the apparatus and increases with increasing height and decreasing flow rate. The magnitude of the scaling up effect is expressed by the scale change factor (SCF), i.e. the ratio of the height of the transfer unit (HTU) of an industrial apparatus to that of a laboratory column. Measurements for elimination of the transverse non-uniformity are proposed. The use of hydraulic model experiments in scaling up studies is illustrated.
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