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The Salt Dependence of the Interferon Regulatory Factor 1 DNA Binding Domain Binding to DNA Reveals Ions Are Localized around Protein and DNA

โœ Scribed by Hargreaves, Victoria V.; Schleif, Robert F.


Book ID
126105383
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
324 KB
Volume
47
Category
Article
ISSN
0006-2960

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## Abstract The mode of action of Hoxa1, like that of most Hox proteins, remains poorly characterized. In an effort to identify functional determinants contributing to the activity of Hoxa1 as a transcription factor, we generated 18 pentapeptide insertion mutants of the Hoxa1 protein and we assayed