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The roles of soluble factors in squalene epoxidation by rat liver microsomes

✍ Scribed by Masahiko Nakamura; Ryo Sato

Book ID
118313998
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
425 KB
Volume
89
Category
Article
ISSN
0006-291X

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Microsomal epoxide hydrolase (mEH) is inducible by a number of xenobiotics. Induction of mEH by certain chemopreventive agents may implicate the protective effect. In contrast, many of carcinogenic agents also induce the enzyme. The hepatotoxicity and mEH expression by methylthiazoles, which are inc