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The role of U5 snRNP in pre-mRNA splicing

โœ Scribed by Newman, Andrew J.


Book ID
111745033
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
115 KB
Volume
16
Category
Article
ISSN
0261-4189

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Mutations in two branch-point sequences (BPS) in intron 3 of the XPC DNA repair gene affect pre-mRNA splicing in association with xeroderma pigmentosum (XP) with many skin cancers (XP101TMA) or no skin cancer (XP72TMA), respectively. To investigate the mechanism of these abnormalities we now report