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The Role of Two SmXXXSm Motifs in the Dimerization of the FGFR3 Transmembrane Domain

โœ Scribed by Mudumbi, Krishna C.; Li, Edwin

Book ID
122287427
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
89 KB
Volume
102
Category
Article
ISSN
0006-3495

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## Abstract Several members of the fibroblast growth factor (FGF) family lack signal peptide (SP) sequences and are present only in trace amounts outside the cell. However, these proteins contain nuclear localization signals (NLS) and accumulate in the cell nucleus. Our studies have shown that full