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The role of tumor necrosis factor-alpha and other cytokines in depression: what dermatologists should know

✍ Scribed by Kannan, Swati; Heller, Misha M; Lee, Eric S; Koo, John YM


Book ID
126608363
Publisher
Informa plc
Year
2011
Tongue
English
Weight
159 KB
Volume
24
Category
Article
ISSN
0954-6634

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Interleukin-18 (IL-18) is not only a co-stimulus for the induction of interferon-gamma but also has direct proinflammatory effects by inducing tumor necrosis factor-alpha (TNF-alpha), IL-1, IL-8 and IL-6. However, the cascade of events leading to induction of cytokines by IL-18 is unclear. The aim o