The role of transforming growth factor (TGF)-β, insulin-like growth factor (IGF)-1, and interleukin (IL)-1 in osteoarthritis and aging of joints
✍ Scribed by I. Blumenfeld; E. Livne
- Book ID
- 114254347
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 82 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0531-5565
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## Abstract This study evaluated the effects of basic fibroblast growth factor, transforming growth factor‐β1, insulin‐like growth factor‐1, and insulin on the incorporation of thymidine and sulfate in human osteoarthritic articular cartilage. Tissue explants were obtained from 11 patients undergoi
Transforming growth factor b1 (TGF-b1) belongs to a family of multifunctional modulatory proteins involved in cell growth, differentiation, development, and wound healing. Although the biological activities of TGF-b1 have been extensively studied, its regulation remains obscure. Here we report the e