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The role of trace elements in the pathogenesis and progress of pilocarpine-induced epileptic seizures

✍ Scribed by J. Chwiej; W. Winiarski; M. Ciarach; K. Janeczko; M. Lankosz; K. Rickers; Z. Setkowicz


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
472 KB
Volume
13
Category
Article
ISSN
1432-1327

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Seizure activity induced by kainic acid (KA) and subsequent neuronal death are thought to be associated with an increase in cytoplasmic free calcium ([Ca2+li) and can be prevented by N-methyl-D-aspartate (NMDA) antagonists. In addition to influx through receptor operated Ca2+ channels the increase i