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The role of Toll-like receptors in immune disorders

✍ Scribed by Uematsu, Satoshi; Akira, Shizuo

Book ID: 120008689
Publisher: Informa plc
Year: 2006
Tongue: English
Weight: 535 KB
Volume: 6
Category: Article
ISSN: 5847-4714
DOI: 10.1517/14712598.6.3.203

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Functional characterization of Toll-like receptors (TLRs) has established that innate immunity is a skillful system that detects invasion of microbial pathogens. Recognition of microbial components by TLRs initiates signal transduction pathways, which triggers expression of genes. These gene product