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The role of toll-like receptor-4 in the development of multi-organ failure following traumatic haemorrhagic shock and resuscitation

✍ Scribed by Lee J. McGhan; Dawn E. Jaroszewski


Book ID
113661592
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
743 KB
Volume
43
Category
Article
ISSN
0020-1383

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## Abstract Severe injury deranges immune function and increases the risk of sepsis and multiple organ failure. Kupffer cells play a major role in mediating posttraumatic immune responses, in part via different Toll‐like receptors (TLR). Although mitogen‐activated protein kinases (MAPK) are key ele