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The role of the TP53 gene during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide

✍ Scribed by E.M. Minicucci; D.A. Ribeiro; G.N. da Silva; M.I.M.C. Pardini; J.C. Montovani; D.M.F. Salvadori


Book ID
113608201
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
704 KB
Volume
63
Category
Article
ISSN
0940-2993

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## Abstract In this study we explored the mutation types of __p16^CDKN2A^__ exon 1 and the corresponding frequencies in experimental rat tongue carcinogenesis. Twenty barrier Sprague–Dawley (SD) rats were divided into the control (__n__ = 5) and experimental group (__n__ = 15), to which 4‐nitroquin