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The role of the spleen in the neuroinvasion of scrapie in mice

✍ Scribed by Kimberlin, Richard H.; Walker, Carol A.


Book ID
122944750
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
709 KB
Volume
12
Category
Article
ISSN
0168-1702

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The involvement of spleen macrophages in the early stages of scrapie pathogenesis was studied by applying the 'macrophage-suicide technique' to scrapie-infected mice. This method comprises critically the intravenous administration to mice of dichloromethylene disphosphonate encapsulated into liposom