𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Role of the Specificity-Determining Loop of the Integrin β Subunit I-like Domain in Autonomous Expression, Association with the α Subunit, and Ligand Binding †

✍ Scribed by Takagi, Junichi; DeBottis, Daniel P.; Erickson, Harold P.; Springer, Timothy A.


Book ID
126210996
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
515 KB
Volume
41
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Role of the αI domain in ligand binding
✍ Elaine M. Corps; Alexis Robertson; M. Joy Dauncey; Peter J. Kilshaw 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 350 KB

## Abstract The I domain of integrin αE was modeled on the crystal structure of that in CD11b and mutated to produce an open (high affinity) or closed (low affinity) conformation. K562 transfectants expressing mutant αE and wild‐type β7 were tested for adhesion to E‐cadherin‐Fc. Downward displaceme

Role of the I-domain in collagen binding
✍ Andreas Kern; Eugene E. Marcantonio 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 2 views

Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified