“Hope” for the liver? Mechanistic insigh
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Gavin E. Arteel
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Article
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2004
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John Wiley and Sons
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English
⚖ 216 KB
👁 1 views
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor superfamily. FXR-null mice exhibit a phenotype similar to Byler disease, an inherited cholestatic liver disorder. In the liver, activation of FXR induces transcription of transpo