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The role of the polycystins in kidney development

โœ Scribed by J. S. van Adelsberg


Publisher
Springer
Year
1999
Tongue
English
Weight
70 KB
Volume
13
Category
Article
ISSN
0931-041X

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Peptides from the PKD repeats of polycys
โœ van Adelsberg, Janet ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 569 KB

Mutations in the PKD1 gene cause the majority of cases of autosomal dominant polycystic kidney disease. The PKD1 gene codes for a protein of unknown function, polycystin-1, that is predicted to be a receptor. Its large extracellular domain contains 16 copies of novel motif, the PKD repeat, that is l