The Nlrp3 inflammasome has been proposed to play an important role in antifungal host defense. However, studies exploring the role of the inflammasome in antifungal host defense have been limited to the direct effects on IL-1b processing. Although IL-1b has important direct effects on the innate imm
✦ LIBER ✦
The role of the inflammasome in cellular responses to toxins and bacterial effectors
✍ Scribed by Barbara Freche; Núria Reig; F. Gisou van der Goot
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 324 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1863-2297
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## Abstract Immune resistance to methylcholanthrene‐induced tumors has two phases, an early specific and a late non‐specific phase. Both phases were found to be T‐cell‐dependent in vivo. Thus, adult thymectomized, irradiated, bone‐marrow‐protected mice bearing H‐1 tumor isografts showed impaired re