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The role of the hippocampus and 5-HT/GABA interaction in the central effects of benzodiazepine receptor ligands

✍ Scribed by M. Nazar; M. Siemiątkowski; A. Członkowska; H. Sienkiewicz-Jarosz; A. Płaźnik


Publisher
Springer
Year
1999
Tongue
English
Weight
153 KB
Volume
106
Category
Article
ISSN
1435-1463

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The effects of a 5-HT1receptor ligand is
✍ G. M. Goodwin; Rosemarie J. Souza; A. R. Green 📂 Article 📅 1986 🏛 Springer 🌐 English ⚖ 557 KB

The effects of 2-(4-(4-(2-pyrimidinyl)-l-piperazinyl)-butyl)-1,2-benzoisothiazol-3(2H)one-1,1-dioxide hydrochloride (isapirone, TVX Q 7821), a putative 5-HT1 receptor antagonist, has been studied on various models of 5-HT receptor sub-type function. In mice TVX Q 7821 produced a dose-dependent inhib