Much progress has been made in identifying genes mutated during the development of colorectal carcinoma. Mutation of the APC gene in particular appears to be fundamental for colorectal tumour initiation. In contrast, loss of expression of E-cadherin appears to be a late event, which may be important
β¦ LIBER β¦
The Role of the E-Cadherin/Catenin Adhesion Complex in the Development and Progression of Cancer
β Scribed by Friedel Nollet; Geert Berx; Frans van Roy
- Book ID
- 115637441
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 450 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1522-4724
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