✦ LIBER ✦

The role of the dopamine transporter (DAT) in the development of PTSD in preschool children

✍ Scribed by Stacy S. Drury; Katherine P. Theall; Bronya J.B. Keats; Michael Scheeringa

Publisher: Springer
Year: 2009
Tongue: English
Weight: 91 KB
Volume: 22
Category: Article
ISSN: 0894-9867
DOI: 10.1002/jts.20475

No coin nor oath required. For personal study only.

✦ Synopsis

Population-based association studies have supported the heritability of posttraumatic stress disorder (PTSD).

This study explored the influence of genetic variation in the dopamine transporter (DAT) 3 untranslated region variable number tandem repeat on the development of PTSD in preschool children exposed to Hurricane Katrina, diagnosed using a developmentally appropriate semistructured interview. A diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition ( DSM-IV; American Psychiatric Association, 1994), total symptoms, and specifically Criterion D symptoms were significantly more likely to be found in children with the 9 allele. This study replicates a previous finding in adults with PTSD. The specificity of this finding to the increased arousal symptoms of Criterion D suggests that dopamine and the DAT allele may contribute to one heritable path in a multifinality model of the development of PTSD.

📜 SIMILAR VOLUMES

Association analysis of the dopamine tra

Association analysis of the dopamine transporter (DAT1)-67A/T polymorphism in bipolar disorder

✍ M.R. Keikhaee; F. Fadai; M.R. Sargolzaee; A. Javanbakht; H. Najmabadi; M. Ohadi 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB 👁 2 views

## Abstract An imbalance in the dopaminergic system in humans has been hypothesized to contribute to the pathogenesis of a number of psychiatric illnesses, including bipolar disorder, schizophrenia, and attention deficit hyperactivity disorder. We performed a case/control study on the __DAT1__ (HUG

Role of dopamine transporter imaging in

Role of dopamine transporter imaging in the diagnosis of atypical tremor disorders

✍ Vicky Marshall; Donald G. Grosset 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 96 KB

Dopamine transporter (DAT) imaging detects presynaptic dopamine neuronal dysfunction and thereby assists differentiation of conditions with and without dopamine deficit. In atypical tremor disorders, DAT imaging can differentiate between Parkinson's disease (PD), where dopamine deficit is demonstrat

The development of inhibitory control in

The development of inhibitory control in preschool children: Effects of “executive skills” training

✍ Sharon M. Dowsett; David J. Livesey 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB 👁 2 views

As one of several processes involved in the executive functioning of the cognitive system, inhibitory control plays a significant role in determining how various mental processes work together in the successful performance of a task. Studies of response inhibition have shown that although 3-year-old

The role of maternal responsivity in the

The role of maternal responsivity in the development of children with intellectual disabilities

✍ Warren, Steven F. ;Brady, Nancy C. 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB

## Abstract There is growing evidence that cumulative exposure to highly responsive parenting styles throughout the early childhood period may provide a variety of important child benefits in terms of language, cognitive, social, and emotional development. We view maternal responsivity as a dynamic

Role of DAT-SPECT in the diagnostic work

Role of DAT-SPECT in the diagnostic work up of Parkinsonism

✍ Christoph Scherfler; Johannes Schwarz; Angelo Antonini; Donald Grosset; Francesc 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 1 views

## Abstract The diagnosis of idiopathic Parkinson's disease (PD) can be achieved with high degrees of accuracy in cases with full expression of classical clinical features. However, diagnostic uncertainty remains in early disease with subtle or ambiguous signs. Functional imaging has been suggested

The development of metasuggestibility in

The development of metasuggestibility in children

✍ Kamala London; Maggie Bruck; Debra Ann Poole; Laura Melnyk 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 134 KB 👁 1 views

## Abstract One component of metasuggestibility is the understanding that a person's statements can influence another person's reports. The purpose of the present study was to examine the development of this understanding in school‐aged children. We produced a short video in which a boy makes a fal