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The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling

✍ Scribed by Povelones, Michael; Nusse, Roel


Book ID
110031206
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
605 KB
Volume
24
Category
Article
ISSN
0261-4189

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## Background: Wnt/wingless (wg) signals are transduced by seven-transmembrane frizzleds (fzs) and the single-transmembrane ldl-receptor-related proteins 5 or 6 (lrp5/6) or arrow. the aminotermini of lrp and fz were reported to associate only in the presence of wnt, implying that wnt ligands form a