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The role of the carboxyl terminus in folding of the serotonin transporter

โœ Scribed by Ali El-Kasaby; Herwig Just; Harald Sitte; Oliver Kudlacek; Michael Freissmuth


Publisher
BioMed Central
Year
2010
Tongue
English
Weight
137 KB
Volume
10
Category
Article
ISSN
1471-2210

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In the present study, we attempted to determine the importance of a 23-amino-acid sequence within the carboxyl terminus of the human insulin receptor (IR) molecule in modulating insulin action in Chinese hamster ovary cells. Stable expression of a minigene encoding the receptor fragment led to an in