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The role of the C-terminus of the insulin B-chain in modulating structural and functional properties of the hormone

✍ Scribed by LEYER, SIGMAR ;GATTNER, HANS-GREGOR ;LEITHÄUSER, MARGOT ;BRANDENBURG, DIETRICH ;WOLLMER, AXEL ;HÖCKER, HARTWIG

Book ID
115099792
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
971 KB
Volume
46
Category
Article
ISSN
0367-8377

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## Abstract Over the last few years the importance of the intracellular C‐terminus in the signaling of G‐protein coupled receptors (GPCR) has become increasingly evident. In an effort to provide a structural framework for biological function, we have determined the conformation of the C‐terminus of