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The role of the activating receptor NKG2D in autoimmunity

✍ Scribed by Tom L. Van Belle; Matthias G. von Herrath


Book ID
116757289
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
170 KB
Volume
47
Category
Article
ISSN
0161-5890

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NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves as a major recognition receptor for detection and elimination of transformed and infected cells and participates in the genesis of several inflammatory diseases. The ligands for NKG2D are self-proteins that a