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The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig

✍ Scribed by Ian A Pullar; John R Boot; Richard J Broadmore; Tina A Eyre; Jane Cooper; Graham J Sanger; Susan Wedley; Stephen N Mitchell


Book ID
113584721
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
299 KB
Volume
493
Category
Article
ISSN
0014-2999

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The 5-HT, agonist 2-methyl-5-HT had previously been shown to enhance the electrically evoked release of L3Hl5-HT from preloaded slices of the guinea pig brain. In the present study, 2-methyld-HT (1 pM) was also found to increase the K' evoked release of i3HI5-HT from preloaded slices of the guinea p