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The role of telomerase in breast cancer

✍ Scribed by K Mokbel

Book ID: 117817569
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 112 KB
Volume: 26
Category: Article
ISSN: 0748-7983
DOI: 10.1053/ejso.1999.0932

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Telomerase is a cellular reverse transcriptase that helps to provide genomic stability in highly proliferative normal, immortal, and tumor cells by maintaining the integrity of the chromosome ends, the telomeres. The activity of telomerase is associated with the majority of malignant human cancers.