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The role of telomerase activity in hepatocellular carcinoma

โœ Scribed by Mitsuo Shimada; Hirofumi Hasegawa; Tomonobu Gion; Tohru Utsunomiya; Ken Shirabe; Kenji Takenaka; Teruhisa Otsuka; Yoshihiko Maehara; Keizo Sugimachi

Book ID
119397020
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
60 KB
Volume
95
Category
Article
ISSN
0002-9270

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Telomerase activity in hepatocellular ca
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Background and Objectives: Activation of telomerase and stabilization of telomeres are considered necessary for immortalization of tumor cells. Telomerase activity was analyzed in 69 hepatocellular carcinomas and adjacent chronic liver disease tissues. The telomerase activity level was examined in r

Significance of telomerase activity in t
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Precise diagnosis of well-differentiated hepatocellular carcinoma (HCC) is sometimes difficult to establish. Telomerase activity was examined by telomeric-repeat-amplification protocol (TRAP) in 37 HCC nodules smaller than 3 cm in diameter, including 24 fine-needle-aspiration biopsy specimens, 22 no