𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The role of targeted BRCA1 / BRCA2 mutation analysis in hereditary breast/ovarian cancer families of Portuguese ancestry

✍ Scribed by Peixoto, A.; Santos, C.; Pinto, P.; Pinheiro, M.; Rocha, P.; Pinto, C.; Bizarro, S.; Veiga, I.; Principe, A.S.; Maia, S.; Castro, F.; Couto, R.; Gouveia, A.; Teixeira, M.R.


Book ID
124078900
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
743 KB
Volume
88
Category
Article
ISSN
0009-9163

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


BRCA1 and BRCA2 mutation analysis in bre
✍ Magdalena Perkowska; Izabela BroΕ»ek; Barbara Wysocka; Karin Haraldsson; Therese πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 66 KB πŸ‘ 2 views

Sixty high-risk breast and/or ovarian cancer families from North-Eastern Poland were screened for germline mutations in BRCA1 (MIM# 113705) and BRCA2 (MIM# 600185), using a combination of protein truncation test, denaturing high-performance liquid chromatography and direct sequencing. Sixteen (27%)

Germline mutations of BRCA1 and BRCA2 in
✍ Hio Chung Kang; Il-Jin Kim; Jae-Hyun Park; Hyuk-Jun Kwon; Yong-Jin Won; Seung Ch πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 140 KB πŸ‘ 2 views

Germline mutations in the BRCA1 and BRCA2 genes are responsible for the predisposition and development of familial breast and/or ovarian cancer. Most mutations of BRCA1 and BRCA2 associated with breast and/or ovarian cancer result in truncated proteins. To investigate the presence of BRCA1 and BRCA2

Hereditary breast and ovarian cancer in
✍ Alexander Liede; Steven A. Narod πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 168 KB

Ethnic differences in cancer incidence and mortality result from differences in genetic and epidemiologic risk factors. Mutations in BRCA1 and BRCA2 account for a small proportion of all breast cancer cases, but for a much higher proportion of cases with a strong family history of breast or ovarian