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The role of surface charge and hydrophobic interaction in the activation of rat liver adenylate cyclase

✍ Scribed by RUBALCAVA, B; GRAJALES, M; CERBON, J; PLIEGO, J

Book ID: 125450343
Publisher: Elsevier Science
Year: 1983
Tongue: English
Weight: 510 KB
Volume: 759
Category: Article
ISSN: 0304-4165
DOI: 10.1016/0304-4165(83)90319-7

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## Abstract The cationic local anaesthetics carbocaine and unpercaine were found to increase the fluoride‐stimulated adenylate cyclase up to a maximum level; above this maximum level further increases in drug concentration inhibited the enzyme. At concentrations where this activity was stimulated,