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The role of substrate specificity and metal binding in defining the activity and structure of an intracellular subtilisin

✍ Scribed by Gamble, Michael; Künze, Georg; Brancale, Andrea; Wilson, Keith S.; Jones, D. Dafydd

Book ID
118446508
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
1016 KB
Volume
2
Category
Article
ISSN
2211-5463

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## Abstract The effect of structural dynamics on enzyme activity and thermostability has thus far only been investigated in detail for the serine protease α‐chymotrypsin (for a recent review see Solá et al., Cell Mol Life Sci 2007, 64(16): 2133–2152). Herein, we extend this type of study to a struc