## Abstract The importance of microRNAs (miRs) in control of gene expression is now clearly recognized. While individual microRNAs are thought to target hundreds of disparate mRNAs via imperfect base pairing, little is known about the characteristics of miR target sites. Here we show that the miRs
β¦ LIBER β¦
The role of site accessibility in microRNA target recognition
β Scribed by Kertesz, Michael; Iovino, Nicola; Unnerstall, Ulrich; Gaul, Ulrike; Segal, Eran
- Book ID
- 109919639
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 479 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1061-4036
- DOI
- 10.1038/ng2135
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## The role of microRNAs in human cancer Non-coding RNAs have recently been identified as important regulatory elements in mammalian and non-mammalian cells. In human cells, the number of microRNAs has been expected to exceed the one thousand mark. In cancer research, the interest in this class of