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The role of sequence in the stabilization of left-handed DNA helices in vitro and in vivo

✍ Scribed by Michael J. McLean; Robert D. Wells

Book ID
119119709
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
1022 KB
Volume
950
Category
Article
ISSN
0167-4781

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## Abstract Aromatic stacking and hydrogen bonding between nucleobases are two of the key interactions responsible for stabilization of DNA double‐helical structures. The present work aims at defining the specific contributions of these interactions to the stability of individual base pairs in DNA.