𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The role of retinoids and their receptors in metabolic disorders

✍ Scribed by Bettina Meissburger; Christian Wolfrum

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
322 KB
Volume
110
Category
Article
ISSN
1438-7697

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Retinoid derivatives are potent regulators of a wide variety of cellular functions through the modulation of nuclear receptor activity. Three distinct families of retinoid receptors have been identified so far, namely retinoic acid receptors, retinoic acid X receptors, and retinoic acid‐related orphan receptors. This review focuses on retinoid signaling and the regulation of metabolic processes by the family of retinoic acid receptors in relation to the development of metabolic disorders.

πŸ“œ SIMILAR VOLUMES

The emerging role of retinoids and retin
The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer
✍ Wilson H. Miller Jr. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 140 KB πŸ‘ 2 views

BACKGROUND. Although significant advances have been made in the treatment of some malignancies, the prognosis of patients with metastatic tumors remains poor. Differentiating agents redirect cells toward their normal phenotype and therefore may reverse or suppress evolving malignant lesions or preve

Glutamate transporter and receptor funct
Glutamate transporter and receptor function in disorders of ammonia metabolism
✍ Butterworth, Roger F. πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 132 KB

## Abstract Disorders of ammonia metabolism including urea cycle enzymopathies, Reye Syndrome, and liver failure are associated with brain edema and severe neurological impairment. Excess blood‐borne ammonia crosses the blood‐brain barrier by diffusion as NH~3~ where it interacts with various cellu

Role of growth factors and their recepto
Role of growth factors and their receptors in gastric ulcer healing
✍ Stefano Milani; Antonio CalabrΓ² πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 479 KB

## Abstract The repair of gastric ulcers requires the reconstitution of epithelial structures and the underlying connective tissue, including vessels and muscle layers. Several growth factors have been implicated in this process, since they are able to regulate important cell functions, such as cel

Role of growth factors and their recepto
Role of growth factors and their receptors in proliferation of microvascular endothelial cells
✍ Agustinus Suhardja; Howard Hoffman πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 129 KB

## Abstract Investigations over the last decade have established the essential role of growth factors and their receptors during angiogenesis. The biological significance of VEGF, EGF, and bFGF is mediated by their receptors, which belong to the family of tyrosine kinase receptors: Flt‐1 (VEGFR‐1),