The role of radioimmunoscintigraphy and computed tomography scan prior to reassessment laparotomy of patients with ovarian carcinoma: A preliminary report
✍ Scribed by Michael W. Method; Aldo N. Serafini; Hervy E. Averette; Michael Rodriguez; Manuel A. Penalver; Bernd-Uwe Sevin
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 768 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
BACKGROUND.
Accurate evaluation of patients with ovarian carcinoma who have completed primary therapy often requires surgical exploration. Radioimmunoscintigraphy (RE) represents an evolving technique that may allow noninvasive detection and localization of persistent or recurrent disease in these patients.
METHODS.
Our prospective, blinded study enrolled patients with normal CA 125 levels and no clinical evidence of disease after primary cytoreductive surgery and cytotoxic chemotherapy for ovarian carcinoma. Each patient underwent RIS using "'Indium-satumomab pendetide (labeled antibody B72.3 to the tumor-associated antigen TAG-72) and abdominalipelvic computed tomography (CT) prior to reassessment laparotomy.