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The role of protein kinase C and the phosphatidylinositol cycle in multidrug resistance in human ovarian cancer cells

✍ Scribed by Lorraine Anderson; Jeffrey Cummings; Tracey Bradshaw; John F. Smyth

Book ID
115782294
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
654 KB
Volume
42
Category
Article
ISSN
0006-2952

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## Abstract The multidrug resistant (MDR) phenotype is often attributed to the activity of ATP‐binding cassette (ABC) transporters such as P‐glycoprotein (ABCB1). Previous work has suggested that modulation of MDR may not necessarily be a single gene trait. To identify factors that contribute to th