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The role of protein binding in the model study of the pharmacokinetics and evaluation of the biological accessability of sulfanilamides

โœ Scribed by A. A. Firsov; G. Ya. Kivman; I. Ya. Geitman; N. P. Neugodova


Book ID
112408892
Publisher
Springer
Year
1979
Tongue
English
Weight
486 KB
Volume
13
Category
Article
ISSN
0091-150X

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## Abstract __Purpose__. To characterize the pharmacokinetics of cetirizine enantiomers in the guinea pig including protein binding in both the guinea pig and human plasma. __Methods__. Plasma concentrations of cetirizine enantiomers in the guinea pig were determined using a LCโ€MS/MS method after