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The role of polyol pathway in high glucose-induced endothelial cell damages

โœ Scribed by Tomokazu Oyama; Yoh Miyasita; Husako Watanabe; Kohji Shirai

Book ID
116405574
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
325 KB
Volume
73
Category
Article
ISSN
0168-8227

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The polyol pathway and glucose 6-phospha
The polyol pathway and glucose 6-phosphate in human endothelial cells cultured in high glucose concentrations
โœ M. Lorenzi; S. Toledo; G. R. Boss; M. J. Lane; D. F. Montisano ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 704 KB

In an attempt to identify the mechanisms underlying the ill effects of high glucose previously described in cultured human endothelial cells, we have investigated in these cells the activity of the polyol pathway and accumulation of glucose 6-phosphate, a powerful agent of non-enzymatic glycosylatio