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The role of PI3K/Akt pathway in β-glucan-induced dendritic cell maturation

✍ Scribed by Jiezhong Chen; Wenyi Gu; Kongnan Zhao

Book ID
116576857
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
114 KB
Volume
11
Category
Article
ISSN
1567-5769

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## Abstract The PI3K‐AKT pathway can mediate diverse biological responses and is crucial for optimal immune responses and lymphocyte development. Deletion of PI3K subunits or AKT leads to blockage of T‐cell development at the TCR‐β checkpoint. Studies with over‐expression of constitutively activate