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The Role of PGE2 in the Differentiation of Dendritic Cells: How Do Dendritic Cells Influence T-Cell Polarization and Chemokine Receptor Expression?

✍ Scribed by Je-Jung Lee; Masao Takei; Shinichi Hori; Yoshiko Inoue; Yukie Harada; Ryuji Tanosaki; Yoshinobu Kanda; Masayuki Kami; Atsushi Makimoto; Shin Mineishi; Hiroyuki Kawai; Akihiro Shimosaka; Yuji Heike; Yoshinori Ikarashi; Hiro Wakasugi; Yoichi Takaue; Tai-Ju Hwang; Hyeoung-Joon Kim; Tadao Kakizoe

Book ID
111843363
Publisher
AlphaMed Press
Year
2002
Tongue
English
Weight
588 KB
Volume
20
Category
Article
ISSN
1066-5099

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Dendritic cells are essential for Th2 differentiation of naΔ± Β¨ve CD4 + T cells in response to aeroallergens, and in recent years it has been well established that these cells play a pivotal role in the initiation phase of allergic asthma. Dendritic cells are also crucial for maintaining eosinophilic