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THE ROLE OF PERFORIN IN TRANSPLANT VASCULAR DISEASE

โœ Scribed by Jonathan C Choy; Alexandra Kerjner; Brian W Wong; Bruce M McManus; David J Granville


Book ID
116342245
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
42 KB
Volume
13
Category
Article
ISSN
1054-8807

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Normal arteries are characterized by a low turnover of endothelial (EC) and smooth muscle cells (SMC). Different mechanisms protect the EC and SMC against apoptosis in the normal artery. In hypertension, SMC replication is increased but this is not counterbalanced by increased apoptosis, resulting i