The role of Pbx1 in T cells
β Scribed by Mayami Sengupta; Laurence Morel
- Book ID
- 107692184
- Publisher
- SP Higher Education Press
- Year
- 2011
- Tongue
- English
- Weight
- 73 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1674-800X
No coin nor oath required. For personal study only.
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## Abstract PreβB cell leukemia transcription factors (PBXs) are important coβfactors for the transcriptional regulation mediated by a number of Hox proteins during embryonic development. It was previously shown that the expression of several __Pbx__ genes is elevated in mouse embryo limb buds and
## Abstract __Hox__ genes contain a homeobox encoding a 60βamino acid DNA binding sequence. The __Hoxa1__ gene (__Hox1.6__, __ERA1__) encodes two alternatively spliced mRNAs that encode distinct proteins, one with the homeodomain (Hoxa1β993), and another protein lacking this domain (Hoxa1β399). The