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The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells

✍ Scribed by Seon-Joo Park; In-Sook Kim

Book ID: 110008862
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 242 KB
Volume: 146
Category: Article
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0706360

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## Abstract Previously, we have shown that the release of AIF from mitochondria is required for As~2~O~3~‐induced cell death in human cervical cancer cells, and that reactive oxygen species (ROS) is necessary for AIF release from mitochondria. In this study, we further investigated the role of MAPK