The role of oxygen free radicals in the destruction of endothelium-derived relaxing factor (EDRF)
✍ Scribed by R. J. Gryglewski
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1987
- Tongue
- English
- Weight
- 98 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1420-908X
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## Abstract Using an extracorporeal circulatory system of fresh blood, the vasodilative effect of endothelium‐derived relaxing factor (EDRF) secreted from vascular endothelium, stimulated by acetylcholine (ACh), was evaluated. The bioassay cascade technique was applied to elucidate the release of E
## Abstract Endothelium‐derived relaxation mediated primarily by endothelium‐derived relaxing factor/nitric oxide (EDRF/NO) is essential in the maintenance of vascular tone. However, little is known about the effects of denervation on EDRF‐mediated relaxation in the microcirculation after reimplant