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The role of oxidative stress in diseases caused by mineral dusts and fibres: Current status and future of prophylaxis and treatment

✍ Scribed by M. Gulumian

Book ID
110243031
Publisher
Springer
Year
1999
Tongue
English
Weight
84 KB
Volume
196
Category
Article
ISSN
0300-8177

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## Abstract Continuously generated hydrogen peroxide (H~2~O~2~) inhibits typical apoptosis and instead initiates a caspase‐independent, apoptosis‐inducing factor (AIF)‐mediated pyknotic cell death. This may be related to H~2~O~2~‐mediated DNA damage and subsequent ATP depletion, although the exact