It is now becoming apparent that cross-talk between two protein lysine modifications, acetylation and ubiquitination, is a critical regulatory mechanism controlling vital cellular functions. The most apparent effect is the inhibition of proteasome-mediated protein degradation by lysine acetylation.
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The role of osteocalcin in the endocrine cross-talk between bone remodelling and energy metabolism
β Scribed by P. Ducy
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 183 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0012-186X
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## Abstract Cyproterone acetate (CA), an antiandrogenic compound, was used in order to investigate the role of testosterone in bone growth processes. The formation of Haversian systems in the growing antlers of whiteβtailed deer (Odocoileus virginianus) were substantially affected by only 3.5 mg of