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The Role of Obesity-associated Loci Identified in Genome-wide Association Studies in the Determination of Pediatric BMI

✍ Scribed by Jianhua Zhao; Jonathan P. Bradfield; Mingyao Li; Kai Wang; Haitao Zhang; Cecilia E. Kim; Kiran Annaiah; Joseph T. Glessner; Kelly Thomas; Maria Garris; Edward C. Frackelton; F. George Otieno; Julie L. Shaner; Ryan M. Smith; Rosetta M. Chiavacci; Robert I. Berkowitz; Hakon Hakonarson; Struan F.A. Grant


Book ID
109969597
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
146 KB
Volume
17
Category
Article
ISSN
1930-7381

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Power of genome-wide association studies
✍ Joseph Pickrell; FranΓ§oise Clerget-Darpoux; Catherine Bourgain πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 336 KB πŸ‘ 2 views

## Abstract Though multiple interacting loci are likely involved in the etiology of complex diseases, early genome‐wide association studies (GWAS) have depended on the detection of the marginal effects of each locus. Here, we evaluate the power of GWAS in the presence of two linked and potentially