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The Role of Nucleation Inhibition in Optical Resolutions with Families of Resolving Agents

✍ Scribed by José W. Nieuwenhuijzen; Reinier F. P. Grimbergen; Carla Koopman; Richard M. Kellogg; Ton R. Vries; Kees Pouwer; Erik van Echten; Bernard Kaptein; Lumbertus A. Hulshof; Quirinius B. Broxterman

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
129 KB
Volume
114
Category
Article
ISSN
0044-8249

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## Abstract The resolution of racemates through their diastereomeric salts can be positively affected by the addition of small amounts of suitable nucleation inhibitors. This discovery is a logical extension of “Dutch Resolution”, in which equimolar amounts of resolving agents that are members of t