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The Role of NQO1 Polymorphisms in the Susceptibility and Chemotherapy Response of Chinese NSCLC Patients

โœ Scribed by Tian, Gang; Wang, Miaomiao; Xu, Xiaogang

Book ID
121566238
Publisher
Springer-Verlag
Year
2014
Tongue
English
Weight
208 KB
Volume
69
Category
Article
ISSN
1085-9195

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## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac